The vaccines really are that good for your personal safety

The clinical and real-world evidence for the vaccines is now pretty clear: They are extremely effective at protecting a person from Covid-19.

The clinical trials put the two-shot Moderna and Pfizer/BioNTech vaccines’ efficacy rates at 95-plus percent and the one-shot Johnson & Johnson vaccine’s at more than 70 percent. All three vaccines also drove the risk of hospitalization and death to nearly zero.

The real-world evidence has backed this up. In Israel, the country with the most advanced vaccination campaign, the data shows that the Pfizer/BioNTech vaccine has been more than 90 percent effective at preventing infections, with even higher rates of blocking symptomatic disease, hospitalization, and death. You can see this in the country’s overall statistics: After Israel almost fully reopened its economy in March, once the majority of the population had at least one dose, daily new Covid-19 cases fell by more than 95 percent. And daily deaths are now in the single digits and, at times, zero.

The research also shows the vaccines are effective against the coronavirus variants that have been discovered so far. While some variants seem better able to get around immunity, the vaccines are so powerful that they still by and large overwhelm and defeat the variants in the end.

It’s this evidence that’s made experts confident the vaccines let them stop worrying about their own Covid-19 risk. “I am fully vaccinated and have resumed normal activities,” Monica Gandhi, an infectious diseases doctor at the University of California San Francisco, told me. “I have gone indoor dining, went to my first movie theater, and would go to a bar if there was an opportunity!”

The diminished concern applies to others who are vaccinated, too. Smith spoke of having her fully vaccinated in-laws visit this coming weekend — “the first time we’ve seen them in person since December 2019.”

There have been some breakthrough Covid-19 cases among those who are vaccinated. But they tend to be milder infections, less likely to transmit, and far from common. “This is less than 0.01 percent of the vaccinated,” Akiko Iwasaki, an immunologist at the Yale School of Medicine, told me, citing CDC data. “So extremely rare!”

To the extent that some experts are still playing it safe for themselves, they cited an abundance of caution — and a lack of interest in certain activities.

“I go out to eat, but still only outdoors. I want to be fully relaxed for a restaurant dining experience. For me, with people I don’t know eating with masks off, I feel safest outside,” Kirsten Bibbins-Domingo, an epidemiologist at UC San Francisco, told me. “I haven’t been to bars, concerts, theaters, but that probably reflects the fact that I’m a rather boring person.”

Some acknowledged that their continuing caution was a habit that needed to be broken: After a year of worrying about the virus, it takes a bit of time to go back to a pre-pandemic mentality. “I am not too concerned about my own safety,” Jorge Salinas, an epidemiologist at the University of Iowa, told me. “I think it is mostly a matter of habits. I think it is okay to go back to restaurants but have continued getting takeout. But whoever is vaccinated and feels ready, I think it is safe for them to do so in most places.”

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Continuing precautions are really about protecting others

The one reason experts consistently cited for continued precautions: the need to protect those who are unvaccinated. “We’ll probably be holding off on any indoors activities for now, since we have an unvaccinated 7-year-old at home,” Smith said. “The risk is low for us to catch and transmit anything to him, but after all this time avoiding indoor venues and being careful, a movie theater or dinner at a restaurant just doesn’t seem worth it when we still have great options with home theater and takeout meals. Once everyone is vaccinated, those will be back in our rotation.”

Some recent research found that the vaccines can reduce the chances of a vaccinated person spreading the virus to others. The CDC summarized one such real-world study for the Pfizer/BioNTech and Moderna vaccines, showing the vaccines stop not just symptoms but overall infections and, therefore, transmission:

Results showed that following the second dose of vaccine (the recommended number of doses), risk of infection was reduced by 90 percent two or more weeks after vaccination. Following a single dose of either vaccine, the participants’ risk of infection with SARS-CoV-2 was reduced by 80 percent two or more weeks after vaccination.

But in the typically cautious worlds of science and public health, experts want to see a bit more research and data before they declare that vaccinated people can throw out their masks and gather in large numbers indoors. (Some experts also said they may continue masking and avoiding crowded indoor spaces during flu season, after such measures seemed to crush the flu in the past year.)

Even if the vaccine proves to reduce transmission, it would still be safer for every person who can get vaccinated to get the shot. And as more people get their shots, it’s also safer to stick to some precautions for their sake.

To that end, experts recommended watching a few figures going forward: the vaccination rate, and daily new cases or hospitalizations. As vaccination rates go up and surpass 50 or 60 percent at a local level, a vaccinated person can feel much more confident going out without worrying about potentially infecting others. And as cases and hospitalizations go down, a vaccinated person can also have confidence that there’s not much virus out there — further shrinking their chances of getting infected and spreading it.

In the meantime, those who are already vaccinated can help speed up the process by encouraging their friends, family, and peers to get the shot. Surveys consistently show that around 1 in 3 unvaccinated people are waiting for others around them to get vaccinated first before they do so. Sharing vaccination stories, then, could give people the push they need.

“I’m very cognizant that while I’m vaccinated, many still are not,” Saskia Popescu, an epidemiologist at George Mason University, told me. “So I’m still vigilant in wearing my mask while out in public running errands, or when interacting with servers [and] other patrons if I go to an outdoor restaurant, even though I’m not really concerned for my own risk of getting sick.”